ClustAssess - Tools for Assessing Clustering

A set of tools for evaluating clustering robustness using proportion of ambiguously clustered pairs (Senbabaoglu et al. (2014) <doi:10.1038/srep06207>), as well as similarity across methods and method stability using element-centric clustering comparison (Gates et al. (2019) <doi:10.1038/s41598-019-44892-y>). Additionally, this package enables stability-based parameter assessment for graph-based clustering pipelines typical in single-cell data analysis.

Last updated 28 days ago

softwaresinglecellrnaseqatacseqnormalizationpreprocessingdimensionreductionvisualizationqualitycontrolclusteringclassificationannotationgeneexpressiondifferentialexpressionbioinformaticsgenomicsmachine-learningparameter-optimizationrobustnesssingle-cellunsupervised-learningcpp

5.68 score 22 stars 18 scripts 495 downloads

bulkAnalyseR - Interactive Shiny App for Bulk Sequencing Data

Given an expression matrix from a bulk sequencing experiment, pre-processes it and creates a shiny app for interactive data analysis and visualisation. The app contains quality checks, differential expression analysis, volcano and cross plots, enrichment analysis and gene regulatory network inference, and can be customised to contain more panels by the user.

Last updated 1 years ago

4.47 score 27 stars 11 scripts 344 downloads

noisyr - Noise Quantification in High Throughput Sequencing Output

Quantifies and removes technical noise from high-throughput sequencing data. Two approaches are used, one based on the count matrix, and one using the alignment BAM files directly. Contains several options for every step of the process, as well as tools to quality check and assess the stability of output.

Last updated 3 years ago

4.13 score 9 stars 1 dependents 5 scripts 208 downloads